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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15B' and Ligand = 'BDBM50528957'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid lipoxygenase ALOX15B


(Rattus norvegicus)		BDBM50528957
PNG
(CHEMBL4570994)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3C#N)c2c(=O)[nH]1
Show InChI InChI=1S/C21H16N6O2/c22-10-14-3-1-2-4-16(14)25-19(28)13-7-5-12(6-8-13)9-15-11-24-18-17(15)20(29)27-21(23)26-18/h1-8,11H,9H2,(H,25,28)(H4,23,24,26,27,29)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
BindingDB Entry DOI: 10.7270/Q29Z98B8
More data for this
Ligand-Target Pair