Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 3' and Ligand = 'BDBM458966'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM458966 ((4-{[2-(4-Bromophenyl)imidazo [1,2-a]pyridin-3-yl]...) Show SMILES Fc1ccccc1C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C25H22BrFN4O/c26-19-10-8-18(9-11-19)24-22(31-12-4-3-7-23(31)28-24)17-29-13-15-30(16-14-29)25(32)20-5-1-2-6-21(20)27/h1-12H,13-17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM458966 ((4-{[2-(4-Bromophenyl)imidazo [1,2-a]pyridin-3-yl]...) Show SMILES Fc1ccccc1C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C25H22BrFN4O/c26-19-10-8-18(9-11-19)24-22(31-12-4-3-7-23(31)28-24)17-29-13-15-30(16-14-29)25(32)20-5-1-2-6-21(20)27/h1-12H,13-17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM458966 ((4-{[2-(4-Bromophenyl)imidazo [1,2-a]pyridin-3-yl]...) Show SMILES Fc1ccccc1C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C25H22BrFN4O/c26-19-10-8-18(9-11-19)24-22(31-12-4-3-7-23(31)28-24)17-29-13-15-30(16-14-29)25(32)20-5-1-2-6-21(20)27/h1-12H,13-17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00378 BindingDB Entry DOI: 10.7270/Q2959NH4
					More data for this Ligand-Target Pair				3D Structure (crystal)