Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 3' and Ligand = 'BDBM458970'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM458970 (US10759794, Example 55) Show SMILES COc1cccc(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(cc2)C(C)C)CC1 Show InChI InChI=1S/C28H31N5O2/c1-20(2)21-10-12-22(13-11-21)27-24(33-14-5-4-8-25(33)30-27)19-31-15-17-32(18-16-31)28(34)23-7-6-9-26(29-23)35-3/h4-14,20H,15-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM458970 (US10759794, Example 55) Show SMILES COc1cccc(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(cc2)C(C)C)CC1 Show InChI InChI=1S/C28H31N5O2/c1-20(2)21-10-12-22(13-11-21)27-24(33-14-5-4-8-25(33)30-27)19-31-15-17-32(18-16-31)28(34)23-7-6-9-26(29-23)35-3/h4-14,20H,15-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair