BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily A member 5' and Ligand = 'BDBM50496407'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily A member 5


(Homo sapiens (Human))		BDBM50496407
PNG
(CHEMBL3127404)
Show SMILES CN1[C@H](CN(Cc2ccc(Cl)cc2)S(=O)(=O)c2cccc(c2)C#N)CCC1=O |r|
Show InChI InChI=1S/C20H20ClN3O3S/c1-23-18(9-10-20(23)25)14-24(13-15-5-7-17(21)8-6-15)28(26,27)19-4-2-3-16(11-19)12-22/h2-8,11,18H,9-10,13-14H2,1H3/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human Kv1.5 ion channel expressed in CHO cells by patch clamp assay

Bioorg Med Chem Lett 24: 1269-73 (2014)


Article DOI: 10.1016/j.bmcl.2014.01.067
BindingDB Entry DOI: 10.7270/Q2930X4D
More data for this
Ligand-Target Pair