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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM396832'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM396832
PNG
(US9981950, Example 39)
Show SMILES Clc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CCC2)nn1
Show InChI InChI=1S/C16H15Cl2N5/c17-14-5-4-13(8-15(14)18)23-10-12(20-21-23)9-22-7-6-19-16(22)11-2-1-3-11/h4-8,10-11H,1-3,9H2
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 7.58n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
TBD


Bioorg Med Chem Lett 18: 3168-72 (2008)


BindingDB Entry DOI: 10.7270/Q2JW8H7X
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM396832
PNG
(US9981950, Example 39)
Show SMILES Clc1ccc(cc1Cl)-n1cc(Cn2ccnc2C2CCC2)nn1
Show InChI InChI=1S/C16H15Cl2N5/c17-14-5-4-13(8-15(14)18)23-10-12(20-21-23)9-22-7-6-19-16(22)11-2-1-3-11/h4-8,10-11H,1-3,9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.58n/an/an/an/an/an/a



Anadys Pharmaceuticals



Assay Description
Cells were split 2-3 times weekly between 1:3 and 1:4. For binding assays and membrane preparations the cell culture medium was removed, cells were w...


Bioorg Med Chem Lett 19: 451-8 (2009)


BindingDB Entry DOI: 10.7270/Q2TH8Q1D
More data for this
Ligand-Target Pair