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Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM409482'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM409482
PNG
(1-(3-Fluoroazetidin-1-yl)-2-[6-(4-fluoro-3-methyl-...)
Show SMILES Cc1cc(ccc1F)-c1cnc2ccn(CC(=O)N3CC(F)C3)c2c1
Show InChI InChI=1S/C19H17F2N3O/c1-12-6-13(2-3-16(12)21)14-7-18-17(22-8-14)4-5-23(18)11-19(25)24-9-15(20)10-24/h2-8,15H,9-11H2,1H3
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PC cid
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UniChem
Article
PubMed
 2.90E+3n/an/an/an/an/an/an/an/a



Janssen Research & Development, LLC

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from recombinant human ERG expressed in HEK293 cell membranes measured after 80 mins by TopCount scintillation analysi...

ACS Med Chem Lett 10: 261-266 (2019)


Article DOI: 10.1021/acsmedchemlett.8b00542
BindingDB Entry DOI: 10.7270/Q2B85CG6
More data for this
Ligand-Target Pair