Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50533688'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50533688 (CHEMBL4476828) Show SMILES Cc1nc2cc(Nc3cc(NC4CCN(CC4)c4ccc(cn4)C#N)c(cn3)C(N)=O)ccc2o1 Show InChI InChI=1S/C25H24N8O2/c1-15-30-21-10-18(3-4-22(21)35-15)32-23-11-20(19(14-28-23)25(27)34)31-17-6-8-33(9-7-17)24-5-2-16(12-26)13-29-24/h2-5,10-11,13-14,17H,6-9H2,1H3,(H2,27,34)(H2,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO-K1 cells after 10 mins by Rb efflux assay				Bioorg Med Chem 24: 4711-4722 (2016) Article DOI: 10.1016/j.bmc.2016.08.007 BindingDB Entry DOI: 10.7270/Q2RJ4NZW
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