BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50062731'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50062731 (CHEMBL3397717) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as inhi...				Bioorg Med Chem Lett 25: 841-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.073 BindingDB Entry DOI: 10.7270/Q2280989
Goethe-University Frankfurt Curated by ChEMBL					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50062731 (CHEMBL3397717) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Activation of wild-type human presenilin-1 stably overexpressed in CHO cells co-expressing wild-type human amyloid precursor protein assessed as amyl...				Bioorg Med Chem Lett 25: 841-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.073 BindingDB Entry DOI: 10.7270/Q2280989
Goethe-University Frankfurt Curated by ChEMBL					More data for this Ligand-Target Pair