Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50436217'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50436217 (CHEMBL2398574) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OCC(O)=O)c(C)c(C)c2O1 Show InChI InChI=1S/C31H52O4/c1-21(2)12-9-13-22(3)14-10-15-23(4)16-11-18-31(8)19-17-27-26(7)29(34-20-28(32)33)24(5)25(6)30(27)35-31/h21-23H,9-20H2,1-8H3,(H,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as decrease in amyloid beta 40 genera...				Bioorg Med Chem Lett 23: 3852-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.070 BindingDB Entry DOI: 10.7270/Q2DF6SMP
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50436217 (CHEMBL2398574) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OCC(O)=O)c(C)c(C)c2O1 Show InChI InChI=1S/C31H52O4/c1-21(2)12-9-13-22(3)14-10-15-23(4)16-11-18-31(8)19-17-27-26(7)29(34-20-28(32)33)24(5)25(6)30(27)35-31/h21-23H,9-20H2,1-8H3,(H,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as decrease in amyloid beta 42 genera...				Bioorg Med Chem Lett 23: 3852-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.070 BindingDB Entry DOI: 10.7270/Q2DF6SMP
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50436217 (CHEMBL2398574) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OCC(O)=O)c(C)c(C)c2O1 Show InChI InChI=1S/C31H52O4/c1-21(2)12-9-13-22(3)14-10-15-23(4)16-11-18-31(8)19-17-27-26(7)29(34-20-28(32)33)24(5)25(6)30(27)35-31/h21-23H,9-20H2,1-8H3,(H,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as decrease in amyloid beta 42 genera...				Bioorg Med Chem Lett 23: 3852-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.070 BindingDB Entry DOI: 10.7270/Q2DF6SMP
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50436217 (CHEMBL2398574) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OCC(O)=O)c(C)c(C)c2O1 Show InChI InChI=1S/C31H52O4/c1-21(2)12-9-13-22(3)14-10-15-23(4)16-11-18-31(8)19-17-27-26(7)29(34-20-28(32)33)24(5)25(6)30(27)35-31/h21-23H,9-20H2,1-8H3,(H,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as increase in amyloid beta 38 genera...				Bioorg Med Chem Lett 23: 3852-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.070 BindingDB Entry DOI: 10.7270/Q2DF6SMP
					More data for this Ligand-Target Pair