Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50477523'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50477523 (CHEMBL246573) Show SMILES C[C@H](NC(=O)CC1CCCCC1)C(=O)NC1c2ccccc2C=NN(C)C1=O |c:24| Show InChI InChI=1S/C21H28N4O3/c1-14(23-18(26)12-15-8-4-3-5-9-15)20(27)24-19-17-11-7-6-10-16(17)13-22-25(2)21(19)28/h6-7,10-11,13-15,19H,3-5,8-9,12H2,1-2H3,(H,23,26)(H,24,27)/t14-,19?/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of gamma secretase assessed as reduction of amyloid beta level in H4 cells				Bioorg Med Chem Lett 17: 4006-11 (2007) Article DOI: 10.1016/j.bmcl.2007.04.082 BindingDB Entry DOI: 10.7270/Q2XD14GF
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