Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50483749'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50483749 (CHEMBL1770886) Show SMILES C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(cn1)C(C)(C)CN1CCCC1 |r| Show InChI InChI=1S/C22H29F2N5O2/c1-15(26-20(30)10-16-8-17(23)11-18(24)9-16)21(31)27-19-12-29(14-25-19)22(2,3)13-28-6-4-5-7-28/h8-9,11-12,14-15H,4-7,10,13H2,1-3H3,(H,26,30)(H,27,31)/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...				Bioorg Med Chem Lett 21: 2631-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.117 BindingDB Entry DOI: 10.7270/Q2K64MX1
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50483749 (CHEMBL1770886) Show SMILES C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(cn1)C(C)(C)CN1CCCC1 |r| Show InChI InChI=1S/C22H29F2N5O2/c1-15(26-20(30)10-16-8-17(23)11-18(24)9-16)21(31)27-19-12-29(14-25-19)22(2,3)13-28-6-4-5-7-28/h8-9,11-12,14-15H,4-7,10,13H2,1-3H3,(H,26,30)(H,27,31)/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassay				Bioorg Med Chem Lett 21: 2631-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.117 BindingDB Entry DOI: 10.7270/Q2K64MX1
					More data for this Ligand-Target Pair