Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50483764'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50483764 (CHEMBL1770907) Show SMILES CCC[C@H](NC1CCc2cc(Cl)ccc2C1)C(=O)Nc1cn(cn1)C(C)(C)CN1CCCC1 |r| Show InChI InChI=1S/C26H38ClN5O/c1-4-7-23(29-22-11-9-19-14-21(27)10-8-20(19)15-22)25(33)30-24-16-32(18-28-24)26(2,3)17-31-12-5-6-13-31/h8,10,14,16,18,22-23,29H,4-7,9,11-13,15,17H2,1-3H3,(H,30,33)/t22?,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassay				Bioorg Med Chem Lett 21: 2637-40 (2011) Article DOI: 10.1016/j.bmcl.2010.12.118 BindingDB Entry DOI: 10.7270/Q2FF3W75
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50483764 (CHEMBL1770907) Show SMILES CCC[C@H](NC1CCc2cc(Cl)ccc2C1)C(=O)Nc1cn(cn1)C(C)(C)CN1CCCC1 |r| Show InChI InChI=1S/C26H38ClN5O/c1-4-7-23(29-22-11-9-19-14-21(27)10-8-20(19)15-22)25(33)30-24-16-32(18-28-24)26(2,3)17-31-12-5-6-13-31/h8,10,14,16,18,22-23,29H,4-7,9,11-13,15,17H2,1-3H3,(H,30,33)/t22?,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...				Bioorg Med Chem Lett 21: 2637-40 (2011) Article DOI: 10.1016/j.bmcl.2010.12.118 BindingDB Entry DOI: 10.7270/Q2FF3W75
					More data for this Ligand-Target Pair