Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50484999'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50484999 (CHEMBL2019012) Show SMILES Fc1ccc(F)c(c1)C1(CCN(CC1)C(=O)C1(CCC1)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClF5NO3S/c24-15-2-5-17(6-3-15)34(32,33)22(18-14-16(25)4-7-19(18)26)10-12-30(13-11-22)20(31)21(8-1-9-21)23(27,28)29/h2-7,14H,1,8-13H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human SH-SY5Y cells co-expressing APP C-terminal fragment SPA4CT assessed as inhibition of amyloid beta 42 productio...				Bioorg Med Chem Lett 22: 3203-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.038 BindingDB Entry DOI: 10.7270/Q2D221GG
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50484999 (CHEMBL2019012) Show SMILES Fc1ccc(F)c(c1)C1(CCN(CC1)C(=O)C1(CCC1)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClF5NO3S/c24-15-2-5-17(6-3-15)34(32,33)22(18-14-16(25)4-7-19(18)26)10-12-30(13-11-22)20(31)21(8-1-9-21)23(27,28)29/h2-7,14H,1,8-13H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human SH-SY5Y cells co-expressing APP C-terminal fragment SPA4CT assessed as inhibition of amyloid beta 40 productio...				Bioorg Med Chem Lett 22: 3203-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.038 BindingDB Entry DOI: 10.7270/Q2D221GG
					More data for this Ligand-Target Pair