Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Pro-glucagon' and Ligand = 'BDBM100812'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-glucagon (Homo sapiens (Human))	BDBM100812 (US8507533, 119) Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Oc1ccc(cc1)-n1cc2ccccc2n1)C1CCCC1 Show InChI InChI=1S/C29H29N3O4/c33-27(34)17-18-30-29(35)22-11-9-21(10-12-22)28(20-5-1-2-6-20)36-25-15-13-24(14-16-25)32-19-23-7-3-4-8-26(23)31-32/h3-4,7-16,19-20,28H,1-2,5-6,17-18H2,(H,30,35)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	103	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.				US Patent US8507533 (2013) BindingDB Entry DOI: 10.7270/Q23R0RGH
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