Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Pro-glucagon' and Ligand = 'BDBM100833'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-glucagon (Homo sapiens (Human))	BDBM100833 (US8507533, 148) Show SMILES CCCC(Oc1cc(C)c(c(C)c1)-n1cc(nn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C25H27F3N4O4/c1-4-5-20(17-6-8-18(9-7-17)24(35)29-11-10-22(33)34)36-19-12-15(2)23(16(3)13-19)32-14-21(30-31-32)25(26,27)28/h6-9,12-14,20H,4-5,10-11H2,1-3H3,(H,29,35)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	125	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.				US Patent US8507533 (2013) BindingDB Entry DOI: 10.7270/Q23R0RGH
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