BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50062743'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50062743 (CHEMBL3397787) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-inducted alkaline phosphatase expression after 24 hrs by plate r...				Bioorg Med Chem 23: 803-9 (2015) Article DOI: 10.1016/j.bmc.2014.12.047 BindingDB Entry DOI: 10.7270/Q2XG9SS2
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062743 (CHEMBL3397787) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo Medical and Dental University Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from human recombinant PR LBD after 24 hrs by liquid scintillation counting analysis				Bioorg Med Chem 23: 803-9 (2015) Article DOI: 10.1016/j.bmc.2014.12.047 BindingDB Entry DOI: 10.7270/Q2XG9SS2
Tokyo Medical and Dental University Curated by ChEMBL					More data for this Ligand-Target Pair