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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50062747'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50062747
PNG
(CHEMBL3397782)
Show SMILES CCN(C(C)=O)c1ccc(cc1)C12CC3CC(CC(C3)(C1)c1ccc(cc1)C#N)C2 |TLB:9:12:15:19.17.18,21:18:15.16.29:13,THB:20:18:15:29.12.13,20:12:15:19.17.18,21:18:15:29.12.13,17:16:13:19.18.20,17:18:15.16.29:13|
Show InChI InChI=1S/C27H30N2O/c1-3-29(19(2)30)25-10-8-24(9-11-25)27-15-21-12-22(16-27)14-26(13-21,18-27)23-6-4-20(17-28)5-7-23/h4-11,21-22H,3,12-16,18H2,1-2H3
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Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Tokyo Medical and Dental University

Curated by ChEMBL


Assay Description
Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-inducted alkaline phosphatase expression after 24 hrs by plate r...

Bioorg Med Chem 23: 803-9 (2015)


Article DOI: 10.1016/j.bmc.2014.12.047
BindingDB Entry DOI: 10.7270/Q2XG9SS2
More data for this
Ligand-Target Pair