Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50086539'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50086539 (4-Methyl-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...) Show SMILES Cc1cc(sc1-c1ccc2NC(C)(C)C=C(C)c2c1)C#N |t:15| Show InChI InChI=1S/C18H18N2S/c1-11-7-14(10-19)21-17(11)13-5-6-16-15(8-13)12(2)9-18(3,4)20-16/h5-9,20H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor (hPR) in a competitive binding assay				Bioorg Med Chem Lett 10: 415-8 (2000) BindingDB Entry DOI: 10.7270/Q2P26ZMF
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50086539 (4-Methyl-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...) Show SMILES Cc1cc(sc1-c1ccc2NC(C)(C)C=C(C)c2c1)C#N |t:15| Show InChI InChI=1S/C18H18N2S/c1-11-7-14(10-19)21-17(11)13-5-6-16-15(8-13)12(2)9-18(3,4)20-16/h5-9,20H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50086539 (4-Methyl-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...) Show SMILES Cc1cc(sc1-c1ccc2NC(C)(C)C=C(C)c2c1)C#N |t:15| Show InChI InChI=1S/C18H18N2S/c1-11-7-14(10-19)21-17(11)13-5-6-16-15(8-13)12(2)9-18(3,4)20-16/h5-9,20H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor (hPR) in a competitive binding assay				Bioorg Med Chem Lett 10: 415-8 (2000) BindingDB Entry DOI: 10.7270/Q2P26ZMF
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50086539 (4-Methyl-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...) Show SMILES Cc1cc(sc1-c1ccc2NC(C)(C)C=C(C)c2c1)C#N |t:15| Show InChI InChI=1S/C18H18N2S/c1-11-7-14(10-19)21-17(11)13-5-6-16-15(8-13)12(2)9-18(3,4)20-16/h5-9,20H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against human progesterone receptor (hPR) in T47D human breast cancer cell line				Bioorg Med Chem Lett 10: 415-8 (2000) BindingDB Entry DOI: 10.7270/Q2P26ZMF
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50086539 (4-Methyl-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...) Show SMILES Cc1cc(sc1-c1ccc2NC(C)(C)C=C(C)c2c1)C#N |t:15| Show InChI InChI=1S/C18H18N2S/c1-11-7-14(10-19)21-17(11)13-5-6-16-15(8-13)12(2)9-18(3,4)20-16/h5-9,20H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Human progesterone receptor (hPR) agonist activity in T47D human breast cancer cell line				Bioorg Med Chem Lett 10: 415-8 (2000) BindingDB Entry DOI: 10.7270/Q2P26ZMF
					More data for this Ligand-Target Pair