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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50198680'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50198680
PNG
(CHEMBL3983437)
Show SMILES Fc1cc(F)cc(Cn2c(ccc2-c2ccc3oc(=O)ccc3c2)C#N)c1
Show InChI InChI=1S/C21H12F2N2O2/c22-16-7-13(8-17(23)10-16)12-25-18(11-24)3-4-19(25)14-1-5-20-15(9-14)2-6-21(26)27-20/h1-10H,12H2
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KEGG

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PC cid
PC sid
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Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Ochanomizu University

Curated by ChEMBL


Assay Description
Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...

Bioorg Med Chem 24: 5602-5610 (2016)


Article DOI: 10.1016/j.bmc.2016.09.020
BindingDB Entry DOI: 10.7270/Q2R49SRM
More data for this
Ligand-Target Pair