Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand/protein 1' and Ligand = 'BDBM474518'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand/protein 1 (Homo sapiens-Homo sapiens (Human))	BDBM474518 (US10882844, Example 1001) Show SMILES CN1CCC(CC1)c1nc2cc(ccc2o1)-c1cccc(COc2cc(OCc3cncc(c3)C#N)c(CN3CCCC[C@H]3C(O)=O)cc2Cl)c1C |r| Show InChI InChI=1S/C41H42ClN5O5/c1-26-31(6-5-7-33(26)30-9-10-37-35(18-30)45-40(52-37)29-11-14-46(2)15-12-29)25-51-39-19-38(50-24-28-16-27(20-43)21-44-22-28)32(17-34(39)42)23-47-13-4-3-8-36(47)41(48)49/h5-7,9-10,16-19,21-22,29,36H,3-4,8,11-15,23-25H2,1-2H3,(H,48,49)/t36-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US10882844 (2021) BindingDB Entry DOI: 10.7270/Q26113F8
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