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Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand/protein 1' and Ligand = 'BDBM50542964'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death 1 ligand/protein 1


(Homo sapiens-Homo sapiens (Human))		BDBM50542964
PNG
(CHEMBL4646486)
Show SMILES C[C@H](O)[C@@H](NCc1cc(Cl)c(OCc2cccc(c2C)-c2ccccc2)cc1OCc1cccc(c1)C#N)C(O)=O |r|
Show InChI InChI=1S/C33H31ClN2O5/c1-21-26(12-7-13-28(21)25-10-4-3-5-11-25)20-41-31-16-30(40-19-24-9-6-8-23(14-24)17-35)27(15-29(31)34)18-36-32(22(2)37)33(38)39/h3-16,22,32,36-37H,18-20H2,1-2H3,(H,38,39)/t22-,32+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.5n/an/an/an/an/an/a



Southern Medical University

Curated by ChEMBL


Assay Description
Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assay

J Med Chem 63: 8338-8358 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00574
BindingDB Entry DOI: 10.7270/Q2JS9V1Q
More data for this
Ligand-Target Pair