Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand 1' and Ligand = 'BDBM363435'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363435 ((S)-2-((5-chloro-2-((5-cyanopyridin-3-yl)methoxy)-...) Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN[C@@H](Cc3ccccn3)C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1 |r| Show InChI InChI=1S/C38H33ClN4O6/c1-24-28(5-4-7-31(24)27-8-9-34-37(15-27)47-12-11-46-34)23-49-36-17-35(48-22-26-13-25(18-40)19-41-20-26)29(14-32(36)39)21-43-33(38(44)45)16-30-6-2-3-10-42-30/h2-10,13-15,17,19-20,33,43H,11-12,16,21-23H2,1H3,(H,44,45)/t33-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair