Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Programmed cell death 1 ligand 1 (Homo sapiens (Human)) | BDBM50239943![]() (CHEMBL4099869 | US9872852, Example 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Curated by ChEMBL | Assay Description Binding affinity to His-tagged PD-L1 (unknown origin) assessed as reduction in PD-L1/PD1-Ig interaction preincubated with PD-L1 for 15 mins followed ... | J Med Chem 60: 5857-5867 (2017) Article DOI: 10.1021/acs.jmedchem.7b00293 BindingDB Entry DOI: 10.7270/Q2765HHP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Programmed cell death 1 ligand 1 (Homo sapiens (Human)) | BDBM50239943![]() (CHEMBL4099869 | US9872852, Example 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de Lisboa Curated by ChEMBL | Assay Description Inhibition of PD-L1 (unknown origin) | J Med Chem 61: 10957-10975 (2018) Article DOI: 10.1021/acs.jmedchem.8b00541 BindingDB Entry DOI: 10.7270/Q2PZ5CHN | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Programmed cell death 1 ligand 1 (Homo sapiens (Human)) | BDBM50239943![]() (CHEMBL4099869 | US9872852, Example 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharmaceuticals | Assay Description All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe... | J Med Chem 51: 4-16 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B42 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |