BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM436148'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM436148
PNG
(US10590105, Example 1034)
Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN[C@H](CO)C(O)=O)cc2Cl)cccc1-c1ccc2nccnc2c1 |r|
Show InChI InChI=1S/C33H28ClN5O5/c1-20-24(3-2-4-26(20)23-5-6-28-29(11-23)38-8-7-37-28)19-44-32-12-31(43-18-22-9-21(13-35)14-36-15-22)25(10-27(32)34)16-39-30(17-40)33(41)42/h2-12,14-15,30,39-40H,16-19H2,1H3,(H,41,42)/t30-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Bristol-Meyers Squibb Company

US Patent


Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...

US Patent US10590105 (2020)


BindingDB Entry DOI: 10.7270/Q2ST7SVD
More data for this
Ligand-Target Pair