BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM436156'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM436156
PNG
(US10590105, Example 1040)
Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN[C@@H](CO)C(O)=O)cc2Cl)cccc1-c1cccn(CCCN2CC[C@@H](O)C2)c1=O |r|
Show InChI InChI=1S/C37H40ClN5O7/c1-24-27(5-2-6-30(24)31-7-3-10-43(36(31)46)11-4-9-42-12-8-29(45)20-42)23-50-35-15-34(49-22-26-13-25(16-39)17-40-18-26)28(14-32(35)38)19-41-33(21-44)37(47)48/h2-3,5-7,10,13-15,17-18,29,33,41,44-45H,4,8-9,11-12,19-23H2,1H3,(H,47,48)/t29-,33+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/an/an/a



Bristol-Meyers Squibb Company

US Patent


Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...

US Patent US10590105 (2020)


BindingDB Entry DOI: 10.7270/Q2ST7SVD
More data for this
Ligand-Target Pair