BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482369'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482369
PNG
(US10919852, Compound TABLE 1.68 | US11708326, Comp...)
Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H](CNC(N)=N)C(O)=O)cc1Cl |r|
Show InChI InChI=1S/C42H48ClN7O6/c1-26-31(5-3-8-37(26)54-16-4-13-50-14-11-30(51)12-15-50)32-6-2-7-34-33(32)9-10-38(34)56-40-19-39(55-25-28-17-27(20-44)21-47-22-28)29(18-35(40)43)23-48-36(41(52)53)24-49-42(45)46/h2-3,5-8,17-19,21-22,30,36,38,48,51H,4,9-16,23-25H2,1H3,(H,52,53)(H4,45,46,49)/t36-,38-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)


BindingDB Entry DOI: 10.7270/Q2RF5Z3R
More data for this
Ligand-Target Pair