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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482372'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482372
PNG
(US10919852, Compound TABLE 1.71 | US11708326, Comp...)
Show SMILES COC(=O)C1(O)CCN(CCCOc2cccc(c2C)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H]([C@@H](C)O)C(O)=O)cc2Cl)C1 |r|
Show InChI InChI=1S/C43H47ClN4O9/c1-26-31(7-5-10-36(26)55-16-6-14-48-15-13-43(53,25-48)42(52)54-3)32-8-4-9-34-33(32)11-12-37(34)57-39-19-38(56-24-29-17-28(20-45)21-46-22-29)30(18-35(39)44)23-47-40(27(2)49)41(50)51/h4-5,7-10,17-19,21-22,27,37,40,47,49,53H,6,11-16,23-25H2,1-3H3,(H,50,51)/t27-,37+,40+,43?/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)


BindingDB Entry DOI: 10.7270/Q2RF5Z3R
More data for this
Ligand-Target Pair