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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482375'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482375
PNG
(US10919852, Compound TABLE 1.74 | US11708326, Comp...)
Show SMILES Cc1c(OCCCN2CC(F)(F)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@H]2CCCC[C@@H]2O)cc1Cl |r|
Show InChI InChI=1S/C42H45ClF2N4O4/c1-27-31(7-5-12-38(27)51-16-6-15-49-25-42(44,45)26-49)32-8-4-9-34-33(32)13-14-39(34)53-41-19-40(52-24-29-17-28(20-46)21-47-22-29)30(18-35(41)43)23-48-36-10-2-3-11-37(36)50/h4-5,7-9,12,17-19,21-22,36-37,39,48,50H,2-3,6,10-11,13-16,23-26H2,1H3/t36-,37+,39+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)


BindingDB Entry DOI: 10.7270/Q2RF5Z3R
More data for this
Ligand-Target Pair