Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482377'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482377 (US10919852, Compound TABLE 1.76 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CC(O)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNCC2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C41H44ClN5O5/c1-26-32(5-3-8-37(26)50-14-4-13-47-23-31(48)24-47)33-6-2-7-35-34(33)10-11-38(35)52-40-17-39(51-25-28-15-27(18-43)19-44-20-28)29(16-36(40)42)21-45-22-30-9-12-41(49)46-30/h2-3,5-8,15-17,19-20,30-31,38,45,48H,4,9-14,21-25H2,1H3,(H,46,49)/t30?,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair