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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482392'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482392
PNG
(US10919852, Compound TABLE 1.91 | US11708326, Comp...)
Show SMILES O[C@H]1CCCC[C@H]1NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CC4(C3)CC(F)(F)C4)c2Cl)cc1OCc1cncc(c1)C#N |r|
Show InChI InChI=1S/C44H46Cl2F2N4O4/c45-35-17-30(22-51-36-9-1-2-10-37(36)53)40(55-23-29-16-28(19-49)20-50-21-29)18-41(35)56-38-13-12-32-31(6-3-7-33(32)38)34-8-4-11-39(42(34)46)54-15-5-14-52-26-43(27-52)24-44(47,48)25-43/h3-4,6-8,11,16-18,20-21,36-38,51,53H,1-2,5,9-10,12-15,22-27H2/t36-,37+,38+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)


BindingDB Entry DOI: 10.7270/Q2RF5Z3R
More data for this
Ligand-Target Pair