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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482417'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482417
PNG
(US10919852, Compound TABLE 1.116 | US11708326, Com...)
Show SMILES CN(C)CCCOc1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@](C)(CO)C(O)=O)cc1Cl |r|
Show InChI InChI=1S/C38H40Cl2N4O6/c1-38(23-45,37(46)47)43-21-26-16-31(39)35(17-34(26)49-22-25-15-24(18-41)19-42-20-25)50-32-12-11-28-27(7-4-8-29(28)32)30-9-5-10-33(36(30)40)48-14-6-13-44(2)3/h4-5,7-10,15-17,19-20,32,43,45H,6,11-14,21-23H2,1-3H3,(H,46,47)/t32-,38-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)


BindingDB Entry DOI: 10.7270/Q2RF5Z3R
More data for this
Ligand-Target Pair