Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482435'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482435 (US10919852, Compound TABLE 1.134) Show SMILES C[C@@](CO)(NCc1cc(Cl)c(O[C@H]2CCc3c2cc(F)cc3-c2cccc(OCCCN3CC(O)C3)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C39H39Cl2FN4O7/c1-39(22-47,38(49)50)45-18-25-11-32(40)36(14-35(25)52-21-24-10-23(15-43)16-44-17-24)53-33-7-6-28-30(12-26(42)13-31(28)33)29-4-2-5-34(37(29)41)51-9-3-8-46-19-27(48)20-46/h2,4-5,10-14,16-17,27,33,45,47-48H,3,6-9,18-22H2,1H3,(H,49,50)/t33-,39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
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