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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482440'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1


(Homo sapiens)		BDBM482440
PNG
(US10919852, Compound TABLE 1.139 | US11708326, Com...)
Show SMILES OC1CN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CN[C@@H]3CCCC[C@@H]3O)cc2Cl)C1 |r|
Show InChI InChI=1S/C41H44Cl2N4O5/c42-34-17-28(22-46-35-9-1-2-10-36(35)49)39(51-25-27-16-26(19-44)20-45-21-27)18-40(34)52-37-13-12-31-30(6-3-7-32(31)37)33-8-4-11-38(41(33)43)50-15-5-14-47-23-29(48)24-47/h3-4,6-8,11,16-18,20-21,29,35-37,46,48-49H,1-2,5,9-10,12-15,22-25H2/t35-,36+,37+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



ChemoCentryx, Inc.

US Patent


Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...

US Patent US10919852 (2021)


BindingDB Entry DOI: 10.7270/Q2RF5Z3R
More data for this
Ligand-Target Pair