Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482464'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482464 (US10919852, Compound TABLE 1.163 | US11708326, Com...) Show SMILES CC1(O)CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3cccc(OCCCN4CCC(F)CC4)c3Cl)cc2OCc2cncc(c2)C#N)CC1 |r| Show InChI InChI=1S/C43H47Cl2FN4O4/c1-43(51)13-18-50(19-14-43)27-31-22-37(44)41(23-40(31)53-28-30-21-29(24-47)25-48-26-30)54-38-10-9-34-33(5-2-6-35(34)38)36-7-3-8-39(42(36)45)52-20-4-15-49-16-11-32(46)12-17-49/h2-3,5-8,21-23,25-26,32,38,51H,4,9-20,27-28H2,1H3/t38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
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