Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1' and Ligand = 'BDBM482551'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death protein 1 (Homo sapiens)	BDBM482551 (US10919852, Compound TABLE 1.250 | US11708326, Com...) Show SMILES Cc1c(OCCCN2CC3(CC(O)C3)C2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CNC[C@H]2CCC(=O)N2)cc1Cl |r| Show InChI InChI=1S/C46H48ClN5O5/c1-29-36(5-3-8-41(29)55-14-4-13-52-27-46(28-52)20-35(53)21-46)37-6-2-7-39-38(37)10-11-42(39)57-44-19-43(56-26-32-16-30(22-48)15-31(17-32)23-49)33(18-40(44)47)24-50-25-34-9-12-45(54)51-34/h2-3,5-8,15-19,34-35,42,50,53H,4,9-14,20-21,24-28H2,1H3,(H,51,54)/t34-,42+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair