BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]' and Ligand = 'BDBM412152'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]


(Homo sapiens (Human))		BDBM412152
PNG
(US10392405, Compound Id 1.016 | US11059834, Compou...)
Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1 |r|
Show InChI InChI=1S/C34H34ClN3O5/c1-22-25(10-7-11-28(22)24-8-3-2-4-9-24)21-43-32-16-31-26(15-29(32)35)19-38-30(34(40)41)12-5-6-13-37-33(39)27-14-23(20-42-31)17-36-18-27/h2-4,7-11,14-18,30,38H,5-6,12-13,19-21H2,1H3,(H,37,39)(H,40,41)/t30-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a


TBA

Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2F192VF
More data for this
Ligand-Target Pair