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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proline-rich AKT1 substrate 1' and Ligand = 'BDBM385996'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proline-rich AKT1 substrate 1


(Homo sapiens (Human))		BDBM385996
PNG
(US10287300, Compound A4 | {2-(4-Chlorophenyl)-2-[4...)
Show SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCCOc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H27ClN6O/c1-25(2)13-17(15-3-5-16(21)6-4-15)26-8-10-27(11-9-26)20-18-19(23-14-24-20)22-7-12-28-18/h3-6,14,17H,7-13H2,1-2H3,(H,22,23,24)
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US Patent
n/an/a 300n/an/an/an/an/an/a



University of Wisconsin at Madison



Assay Description
A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...

J Med Chem 51: 7243-52 (2008)


BindingDB Entry DOI: 10.7270/Q26M394B
More data for this
Ligand-Target Pair