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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proline-rich AKT1 substrate 1' and Ligand = 'BDBM386002'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proline-rich AKT1 substrate 1


(Homo sapiens (Human))		BDBM386002
PNG
(Dimethyl-[2-[4-(5,6,7,8-tetrahydro-pyrido[2,3-d]py...)
Show SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCCCc12)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H29F3N6/c1-29(2)14-19(16-5-7-17(8-6-16)22(23,24)25)30-10-12-31(13-11-30)21-18-4-3-9-26-20(18)27-15-28-21/h5-8,15,19H,3-4,9-14H2,1-2H3,(H,26,27,28)
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US Patent
n/an/a 62n/an/an/an/an/an/a



University of Wisconsin at Madison



Assay Description
A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...

J Med Chem 51: 7243-52 (2008)


BindingDB Entry DOI: 10.7270/Q26M394B
More data for this
Ligand-Target Pair