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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proline-rich AKT1 substrate 1' and Ligand = 'BDBM386003'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proline-rich AKT1 substrate 1


(Homo sapiens (Human))		BDBM386003
PNG
(2-[4-(7,8-Dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-...)
Show SMILES NCC(N1CCN(CC1)c1ncnc2NCCOc12)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C19H23F3N6O/c20-19(21,22)14-3-1-13(2-4-14)15(11-23)27-6-8-28(9-7-27)18-16-17(25-12-26-18)24-5-10-29-16/h1-4,12,15H,5-11,23H2,(H,24,25,26)
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n/an/a 300n/an/an/an/an/an/a



University of Wisconsin at Madison



Assay Description
A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...

J Med Chem 51: 7243-52 (2008)


BindingDB Entry DOI: 10.7270/Q26M394B
More data for this
Ligand-Target Pair