Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proline-rich AKT1 substrate 1' and Ligand = 'BDBM386006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proline-rich AKT1 substrate 1 (Homo sapiens (Human))	BDBM386006 (2-(4-Chloro-phenyl)-2-[4-(6,7-dihydro-5H-pyrrolo[2...) Show SMILES NCC(N1CCN(CC1)c1ncnc2NCCc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H23ClN6/c19-14-3-1-13(2-4-14)16(11-20)24-7-9-25(10-8-24)18-15-5-6-21-17(15)22-12-23-18/h1-4,12,16H,5-11,20H2,(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin at Madison					Assay Description A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...				J Med Chem 51: 7243-52 (2008) BindingDB Entry DOI: 10.7270/Q26M394B
					More data for this Ligand-Target Pair