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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proline-rich AKT1 substrate 1' and Ligand = 'BDBM386056'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proline-rich AKT1 substrate 1


(Homo sapiens (Human))		BDBM386056
PNG
(4-(4-(1-(4-chloro-3-fluorophenyl)-2-(dimethylamino...)
Show SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCC(=O)Nc12)c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C20H25ClFN7O/c1-27(2)11-16(13-3-4-14(21)15(22)9-13)28-5-7-29(8-6-28)20-18-19(24-12-25-20)23-10-17(30)26-18/h3-4,9,12,16H,5-8,10-11H2,1-2H3,(H,26,30)(H,23,24,25)
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US Patent
n/an/a 300n/an/an/an/an/an/a



University of Wisconsin at Madison



Assay Description
A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...

J Med Chem 51: 7243-52 (2008)


BindingDB Entry DOI: 10.7270/Q26M394B
More data for this
Ligand-Target Pair