Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50508980'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50508980 (CHEMBL4584206) Show SMILES F[C@@H]1CCN(C1)C(=O)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C20H19FN2O2/c21-16-9-10-22(13-16)19(24)17-8-4-7-15-12-23(20(25)18(15)17)11-14-5-2-1-3-6-14/h1-8,16H,9-13H2/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assay				J Med Chem 62: 7874-7884 (2019) Article DOI: 10.1021/acs.jmedchem.9b00642 BindingDB Entry DOI: 10.7270/Q2FB5682
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