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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM240978'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))
BDBM240978
PNG
(US9409892, 73)
Show SMILES C[C@](O)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O |r|
Show InChI InChI=1S/C21H17N3O6/c1-21(29,20(27)28)11-23-19(26)17-18(25)14-8-7-13(9-15(14)16(10-22)24-17)30-12-5-3-2-4-6-12/h2-9,25,29H,11H2,1H3,(H,23,26)(H,27,28)/t21-/m0/s1
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US Patent
n/an/a 740n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair