BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM240985'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))
BDBM240985
PNG
(US9409892, 80)
Show SMILES OC(=O)CCCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H17N3O5/c22-12-17-16-11-14(29-13-5-2-1-3-6-13)8-9-15(16)20(27)19(24-17)21(28)23-10-4-7-18(25)26/h1-3,5-6,8-9,11,27H,4,7,10H2,(H,23,28)(H,25,26)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 140n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair