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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM385749'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM385749
PNG
(N-[5-(4- cyanophenyl)- [1,2,4]triazolo[1,5- a]pyri...)
Show SMILES O=C(Cc1ccccc1)Nc1cc(-c2ccc(cc2)C#N)n2ncnc2c1
Show InChI InChI=1S/C21H15N5O/c22-13-16-6-8-17(9-7-16)19-11-18(12-20-23-14-24-26(19)20)25-21(27)10-15-4-2-1-3-5-15/h1-9,11-12,14H,10H2,(H,25,27)
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n/an/a 42n/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...

Bioorg Med Chem 16: 7424-8 (2008)


BindingDB Entry DOI: 10.7270/Q2QJ7KMD
More data for this
Ligand-Target Pair