Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM385809'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM385809 (US10287286, Example 211) Show SMILES Cc1nc(nc(C)c1-c1cccc2ncnn12)C#N |(3.19,-.77,;1.85,,;1.85,1.54,;.52,2.37,;-.82,1.54,;-.82,,;-2.15,-.77,;.52,-.77,;.52,-2.31,;1.85,-3.08,;1.85,-4.62,;.52,-5.39,;-.82,-4.62,;-2.28,-5.1,;-3.19,-3.85,;-2.28,-2.6,;-.82,-3.08,;.52,3.91,;.52,5.45,)| Show InChI InChI=1S/C13H10N6/c1-8-13(9(2)18-11(6-14)17-8)10-4-3-5-12-15-7-16-19(10)12/h3-5,7H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...				Bioorg Med Chem 16: 7424-8 (2008) BindingDB Entry DOI: 10.7270/Q2QJ7KMD
					More data for this Ligand-Target Pair