Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM50239890'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50239890 (CHEMBL4095005 | US10287286, Example 4) Show SMILES Cc1cc(-c2ccc(cc2)C#N)n2ncnc2c1 Show InChI InChI=1S/C14H10N4/c1-10-6-13(18-14(7-10)16-9-17-18)12-4-2-11(8-15)3-5-12/h2-7,9H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Inc. Curated by ChEMBL					Assay Description Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...				J Med Chem 60: 5663-5672 (2017) Article DOI: 10.1021/acs.jmedchem.7b00352 BindingDB Entry DOI: 10.7270/Q2GQ70XZ
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50239890 (CHEMBL4095005 | US10287286, Example 4) Show SMILES Cc1cc(-c2ccc(cc2)C#N)n2ncnc2c1 Show InChI InChI=1S/C14H10N4/c1-10-6-13(18-14(7-10)16-9-17-18)12-4-2-11(8-15)3-5-12/h2-7,9H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...				Bioorg Med Chem 16: 7424-8 (2008) BindingDB Entry DOI: 10.7270/Q2QJ7KMD
					More data for this Ligand-Target Pair