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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM50507409'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM50507409
PNG
(CHEMBL4476576)
Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccn(n2)-c2ccccc2)c1=O
Show InChI InChI=1S/C20H18N4O6/c25-16(26)8-21-19(28)17-18(27)14-10-30-11-15(14)23(20(17)29)9-12-6-7-24(22-12)13-4-2-1-3-5-13/h1-7,27H,8-11H2,(H,21,28)(H,25,26)
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n/an/a 3.20n/an/an/an/an/an/a



Merck & Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...

ACS Med Chem Lett 9: 1193-1198 (2018)


Article DOI: 10.1021/acsmedchemlett.8b00274
BindingDB Entry DOI: 10.7270/Q2MG7SSH
More data for this
Ligand-Target Pair