Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM197565'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM197565 (US9216968, 165 | US9732066, 165) Show SMILES Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(nc12)N1CCC1 Show InChI InChI=1S/C26H21ClF3N5O2/c1-14-19(27)8-4-9-20(14)32-24(37)17-12-15(13-21-22(17)34-25(33-21)35-10-5-11-35)31-23(36)16-6-2-3-7-18(16)26(28,29)30/h2-4,6-9,12-13H,5,10-11H2,1H3,(H,31,36)(H,32,37)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
NIPPON SHINY AKU CO., LTD. US Patent					Assay Description mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...				US Patent US9732066 (2017) BindingDB Entry DOI: 10.7270/Q2K35WSW
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM197565 (US9216968, 165 | US9732066, 165) Show SMILES Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(nc12)N1CCC1 Show InChI InChI=1S/C26H21ClF3N5O2/c1-14-19(27)8-4-9-20(14)32-24(37)17-12-15(13-21-22(17)34-25(33-21)35-10-5-11-35)31-23(36)16-6-2-3-7-18(16)26(28,29)30/h2-4,6-9,12-13H,5,10-11H2,1H3,(H,31,36)(H,32,37)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
NIPPON SHINYAKU CO., LTD. US Patent					Assay Description mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...				US Patent US9216968 (2015) BindingDB Entry DOI: 10.7270/Q2KS6QCQ
					More data for this Ligand-Target Pair