Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM197593'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM197593 (US9216968, 193 | US9732066, 193) Show SMILES CC(C)OCCNc1nc2c(cc(NC(=O)c3cc(Cl)ccc3Cl)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C Show InChI InChI=1S/C27H26Cl3N5O3/c1-14(2)38-10-9-31-27-34-23-13-17(32-25(36)18-11-16(28)7-8-21(18)30)12-19(24(23)35-27)26(37)33-22-6-4-5-20(29)15(22)3/h4-8,11-14H,9-10H2,1-3H3,(H,32,36)(H,33,37)(H2,31,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
NIPPON SHINY AKU CO., LTD. US Patent					Assay Description mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...				US Patent US9732066 (2017) BindingDB Entry DOI: 10.7270/Q2K35WSW
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM197593 (US9216968, 193 | US9732066, 193) Show SMILES CC(C)OCCNc1nc2c(cc(NC(=O)c3cc(Cl)ccc3Cl)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C Show InChI InChI=1S/C27H26Cl3N5O3/c1-14(2)38-10-9-31-27-34-23-13-17(32-25(36)18-11-16(28)7-8-21(18)30)12-19(24(23)35-27)26(37)33-22-6-4-5-20(29)15(22)3/h4-8,11-14H,9-10H2,1-3H3,(H,32,36)(H,33,37)(H2,31,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
NIPPON SHINYAKU CO., LTD. US Patent					Assay Description mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...				US Patent US9216968 (2015) BindingDB Entry DOI: 10.7270/Q2KS6QCQ
					More data for this Ligand-Target Pair